Item – Theses Canada

OCLC number
1019459604
Link(s) to full text
LAC copy
Author
Farmer, Sarah Linda.
Title
The Effectiveness of Modified Fat Breast Milk for the Treatment of Chylothorax in Infants Following Cardiothoracic Surgery.
Degree
M.S.N. -- University of Toronto, 2011
Publisher
Ottawa : Library and Archives Canada = Bibliothèque et Archives Canada, 2012.
Description
1 online resource
Notes
Includes bibliographical references.
Abstract
<?Pub Inc> Background: Chylothorax occurs in ~4 % of children undergoing cardiac surgery. Treatment requires transition to a medium chain triglyceride (MCT) based formula. Provision of breast milk (EBM) is discontinued due to the presence of long chain triglycerides. Objective: To determine the effectiveness of a modified fat breast milk for the treatment of chylothorax in comparison to an MCT formula. Methods: Infants with chylothorax were eligible. Treatment infants (n=8) received EBM that had been modified by removing the fat layer (centrifugation) from EBM and adding MCT and nutrients to provide 67 kcal/ml and 11 g/100 ml protein. Control infants (n=8) received an MCT formula. Results: Volume of chest tube drainage was not different (p<0.40). Treatment infants experienced declines in mean weight (p<0.006), length (p<0.013) and head circumference (p<0.008) z-scores. Conclusion: Modified fat breast milk allowed for successful resolution of chylothorax. Strategies to address poor growth, however, need to be tested before clinical adoption of this novel treatment.
ISBN
9780494823552
0494823550